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Electric and magnetic fields and health

index/glossary | EMFs At A Glance | EMF The Facts (pdf)
  • What are EMFs
    • Terminology – an introduction
    • Electric fields
    • Magnetic fields
    • Units for measuring EMFs
    • Measuring and calculating EMFs
      • “EMF Commercial”
    • Adding fields together
    • Radiofrequencies
    • Screening EMFs
  • Sources
    • Overhead power lines
      • Fields from specific power lines
        • 400 kV
        • 400 kV – specific cases
        • 275 kV
        • 132 kV
        • 66 kV
        • 33 kV
        • 11 kV
        • 400 V/230 V
        • Replacing a 132 kV line with a 400 kV line
      • Summaries of fields from all power lines
      • Factors affecting the field from a power line
        • Voltage
        • Current
        • Clearance
        • Height above ground
        • Conductor bundle
        • Phasing
        • Balance between circuits
        • Balance within circuit
        • Ground resistivity
        • Two parallel lines
      • Calculating and measuring fields from power lines
        • Geometries of power lines
        • Raw data
        • On-line calculator
      • Fields from power lines – more detail on the physics
        • Field lines from a power line
        • The direction of the field from a power line
        • Power law variations in the field from a power line
      • Statistics of power line fields
    • Underground power cables
      • Different types of underground cable
      • Fields from cables in tunnels
      • Gas Insulated Lines (GIL)
      • Underground cables with multiple conductors
      • Effect of height on fields from underground cables
      • Screening fields from underground cables
    • Low-voltage distribution
      • UK distribution wiring
      • USA distribution wiring
    • House wiring
    • Substations
      • National Grid substations
        • Static Var Compensators
      • Sealing-end compounds
      • Distribution substations
      • Final distribution substations
        • Indoor substations
    • Transport
      • EMFs from electric trains (UK)
      • EMFs from cars
    • Appliances
    • Electricity meters
      • Smart meters
      • Traditional meters
    • Occupational exposures
      • Live-line work
      • Static Var Compensators
      • Occupational exposures on pylons
    • Field levels and exposures
      • Personal exposure
      • Other factors that vary with magnetic fields
      • Fields greater than 0.2 or 0.4 µT
    • Screening EMFs
      • Screening fields from underground cables
      • EMF Reduction Devices
  • Known effects
    • Induced currents and fields
    • Microshocks
      • Control of microshocks in the UK
      • Microshocks from bicycles
      • Bees and microshocks
    • EMFs and medical devices
      • Standards relating to pacemakers and other AIMDs
    • Effects of EMFs on equipment
  • Research
    • Types of research
    • Epidemiology
    • Animal and laboratory experiments
    • Mechanisms
    • Specific studies
      • UKCCS
      • CCRG
      • French Geocap study
      • CEGB cohort
      • Imperial College study
  • Current evidence on health
    • Childhood leukaemia
      • Survival from childhood leukaemia
      • Childhood leukaemia and Downs
      • Childhood leukaemia and night-time exposure
      • The “contact current” hypothesis
    • Other health effects
    • Scientific review bodies
      • WHO
      • IARC
    • Electric fields and ions
    • Comparing EMFs to other issues
  • Exposure limits for people
    • Limits in the UK
    • Limits in the EU
    • Limits in the USA
    • Limits in the rest of the world
    • Limits from specific organisations
      • ICNIRP 1998
      • ICNIRP 2010
      • NRPB 1993
      • NRPB 2004
      • EU 2004
      • EU 2013
  • Policy
    • UK policy
      • Power lines and property – UK
    • Compliance with exposure limits
    • European EMF policy
    • Precaution
    • SAGE
      • SAGE First Interim Assessment
        • Government response to SAGE First Interim Assessment
      • SAGE Second Interim Assessment
        • Government response to SAGE Second Interim Assessment
        • SAGE Second Interim Assessment – the full list of recommendations
  • Finding out more
    • EMF measurement and commercial services
    • Links
    • Literature
    • Contact us
  • Static fields
    • Static fields – the expert view
You are here: Home / Research / Animal and laboratory experiments

Animal and laboratory experiments

Experiments in the laboratory, on whole animals or on cells, are one of the three main strands of evidence used to assess health effects, alongside epidemiology and consideration of mechanisms.

Broadly speaking, laboratory studies do not support there being health effects of EMFs.  The suggestions that there are health effects come mainly from the epidemiology.

Experiments on whole animals

Experiments on whole animals, mice and rats in particular, are a standard way of assessing whether an agent causes cancer.  Scientists set high store on these experiments.  Over the years, most agents that cause cancer in humans have also done so in animals, and few agents that have been negative on animals have turned out to be positive on humans.  So results from experiments on animals are regarded as a strong pointer to likely effects or absence of effects in humans.

Several such experiments have been performed with normal mice and rats, several more with animals genetically modified to make them more sensitive, and even more looking for combined effects of EMFs and other agents.  These experiments have failed to find effects on cancer.  See more detail on these studies.  This is a strong piece of evidence against EMFs causing cancer, but it is not conclusive - see below.

Experiments on cells

photo of cell experimentLiterally hundreds, probably thousands, of experiments have been performed "in vitro" - that is, looking for effects of EMFs on cells or tissues.  Many of these studies have reported positive findings.  But when other scientists have tried to replicate these results, they have usually been unable to do so.

Some scientists are not particularly bothered by this failure to replicate results.  They believe the results could be dependent on very specific circumstances, and the replication did not reproduce exactly those circumstances.

But many scientists, and in particular the authoritative scientific review groups, look at the totality of the results and see a failure to produce any robust, replicable result.  Further, the continued failure to replicate reported results makes scientists, quite properly, more sceptical each time a new finding is reported.

Could EMFs cause cancer despite the negative animal studies?

Broadly speaking, for EMFs,

  • epidemiology has found an association in humans between EMFs and childhood leukaemia
  • Laboratory studies have failed to show that EMFs cause cancer, in particular in mice and rats

Normally, we would regard the negative animal studies as strong evidence against EMFs causing cancer.  But could it be possible for EMFs to cause cancer in humans despite not doing so in laboratory animals?  There are two ways that in principle this could happen.

Overall, the negative evidence from the laboratory remains a strong piece of evidence against EMFs causing cancer.  But it cannot be conclusive.

The wrong animal model

Mice and rats are usually pretty good models for testing cancer.  Most agents that cause cancer in humans will cause at least one type of cancer in mice and rats.  And EMFs have been tested not just on normal rodents but on rodents genetically modified to make them particularly sensitive to leukaemia.  But mice and rats do not develop the type of leukaemia that is commonest in children, Acute Lymphoblastic Leukaemia (ALL).  So it is theoretically possible that mice and rats do not get cancer when exposed to EMFs because the mechanism is very precise to this particular form of leukaemia.

The wrong exposure

The fields that are used in laboratory studies tend to be fairly straightforward sinewaves at 50 Hz or 60 Hz.  Sometimes they have been intermittent as well as continuous, and sometimes laboratory studies have used particular polarisations or combinations of AC and DC fields.  But real-life exposures of humans are more complicated - they involve harmonics, transients, intermittency, and variable polarisation and direction.  So it is theoretically possible that the effect depends on some very particular characteristic of the exposure which occurs for humans in real life but has not been reproduced in the laboratory.

See also:

  • overview of all the different types of research
  • epidemiology
  • mechanisms

Latest news

  • New publication on cancer incidence from the UK electricity industry Cohort Study August 27, 2019
  • How has the reported risk for childhood leukaemia changed over time? February 11, 2019
  • Media stories about microshocks in children’s playground September 10, 2018
  • New studies on leukaemia and distance from power lines June 1, 2018
older news

Contact Us

To contact the electricity industry’s EMF Unit Public Information Line (UK only):
telephone 0845 7023270 or email [email protected].

See Contact us for more contact details including our privacy policy.

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Navigation
  • What are EMFs
    • Terminology – an introduction
    • Electric fields
    • Magnetic fields
    • Units for measuring EMFs
    • Measuring and calculating EMFs
      • “EMF Commercial”
    • Adding fields together
    • Radiofrequencies
    • Screening EMFs
  • Sources
    • Overhead power lines
      • Fields from specific power lines
        • 400 kV
        • 400 kV – specific cases
        • 275 kV
        • 132 kV
        • 66 kV
        • 33 kV
        • 11 kV
        • 400 V/230 V
        • Replacing a 132 kV line with a 400 kV line
      • Summaries of fields from all power lines
      • Factors affecting the field from a power line
        • Voltage
        • Current
        • Clearance
        • Height above ground
        • Conductor bundle
        • Phasing
        • Balance between circuits
        • Balance within circuit
        • Ground resistivity
        • Two parallel lines
      • Calculating and measuring fields from power lines
        • Geometries of power lines
        • Raw data
        • On-line calculator
      • Fields from power lines – more detail on the physics
        • Field lines from a power line
        • The direction of the field from a power line
        • Power law variations in the field from a power line
      • Statistics of power line fields
    • Underground power cables
      • Different types of underground cable
      • Fields from cables in tunnels
      • Gas Insulated Lines (GIL)
      • Underground cables with multiple conductors
      • Effect of height on fields from underground cables
      • Screening fields from underground cables
    • Low-voltage distribution
      • UK distribution wiring
      • USA distribution wiring
    • House wiring
    • Substations
      • National Grid substations
        • Static Var Compensators
      • Sealing-end compounds
      • Distribution substations
      • Final distribution substations
        • Indoor substations
    • Transport
      • EMFs from electric trains (UK)
      • EMFs from cars
    • Appliances
    • Electricity meters
      • Smart meters
      • Traditional meters
    • Occupational exposures
      • Live-line work
      • Static Var Compensators
      • Occupational exposures on pylons
    • Field levels and exposures
      • Personal exposure
      • Other factors that vary with magnetic fields
      • Fields greater than 0.2 or 0.4 µT
    • Screening EMFs
      • Screening fields from underground cables
      • EMF Reduction Devices
  • Known effects
    • Induced currents and fields
    • Microshocks
      • Control of microshocks in the UK
      • Microshocks from bicycles
      • Bees and microshocks
    • EMFs and medical devices
      • Standards relating to pacemakers and other AIMDs
    • Effects of EMFs on equipment
  • Research
    • Types of research
    • Epidemiology
    • Animal and laboratory experiments
    • Mechanisms
    • Specific studies
      • UKCCS
      • CCRG
      • French Geocap study
      • CEGB cohort
      • Imperial College study
  • Current evidence on health
    • Childhood leukaemia
      • Survival from childhood leukaemia
      • Childhood leukaemia and Downs
      • Childhood leukaemia and night-time exposure
      • The “contact current” hypothesis
    • Other health effects
    • Scientific review bodies
      • WHO
      • IARC
    • Electric fields and ions
    • Comparing EMFs to other issues
  • Exposure limits for people
    • Limits in the UK
    • Limits in the EU
    • Limits in the USA
    • Limits in the rest of the world
    • Limits from specific organisations
      • ICNIRP 1998
      • ICNIRP 2010
      • NRPB 1993
      • NRPB 2004
      • EU 2004
      • EU 2013
  • Policy
    • UK policy
      • Power lines and property – UK
    • Compliance with exposure limits
    • European EMF policy
    • Precaution
    • SAGE
      • SAGE First Interim Assessment
        • Government response to SAGE First Interim Assessment
      • SAGE Second Interim Assessment
        • Government response to SAGE Second Interim Assessment
        • SAGE Second Interim Assessment – the full list of recommendations
  • Finding out more
    • EMF measurement and commercial services
    • Links
    • Literature
    • Contact us
  • Static fields
    • Static fields – the expert view